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NY 11206 Get Directions. Tried many types of medicines the only thing that works for me is Paregoric. I loved it, sleeping is a bit of an issue some days but not all. It does its job of killing a migraine that could last me for days Directions I have tried standard treatments for this condition and nothing has worked except Norco 10 325 twice a day and Tramadol 100 mg two times a day This.